Do high saturated fat diets lead to heart disease? | Peter Attia and Don Layman
Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): https://bit.ly/3SZ1FaS Watch the full episode: …
source
February 28, 2026
Headlines
🧐🤔
🦧
Not as good for you as poon, I think Dr. Attia would agree!
Understand LDL better! There are particle sizes and higher LDL is not that bad if they are larger in size. Know your other blood markers to find out if you are metabolically healthy (low triglycerides, good BP, low BMI, low belly circumference, etc.).
About 20 years ago or so, a good friend of mine, also about 13 years older than me, had a heart attack at age 52. He survived. What's interesting is that he was a vegan. He never smoked or drank alcohol. Was tall and slender. It's been some time, but I remembered that his total cholesterol was 173 and HDL was 23. I wish I knew what his LDL and triglycerides were. But, when I had dinner at his house, he ate a lot of ultraprocessed so-called veggie foods like veggie burgers, from Morning Star, as well as veggie cheese. Things like that. All ultraprocessed foods. I'm glad I quit eating all that stuff years ago. I eat whole foods now.
They did not purplish the study because it was so flawed in every way. 83 % lose of people in the study is one of the major problems.
THE STARVATION STUDY DID SHOW US WHY 99% OF PORTION CONTROL DIETS FAIL AND WHY INTERMITTENT FASTING REMAINS THE BEST OPTION FOR MOST PEOPLE LOOKING TO LOSE FAT AND IMPROVE HEALTH.
AS USUAL, ONE SIZE OR ONE DIET DOES NOT FIT ALL.
STUDIES LASTING LESS THAN 20 YEARS HAVE LESS PREDICTIVE VALUE
SOME WITH HDL ABOVE 70 MAY HAVE THE LEAST CVD.
Its all about Mitochondria and Inslulin resistance.wat gras fed butter C15 C17 lamp high fat gras fed Wild salmon,stay away from Sigar and carbs..
Tg should be under 80 Hdl more than 50 Lp a once in ur life is VERY IMPORTANT Crp less than 2..
F. Insulin under 8.
Ldl doesnt matter if u keep your Insulin under 8 best is 6 or less.
Stay away from some Dr on internebr they get money from big Pharmas. WAKE UP
I think the problem for all fats is how they are digested and the heavy lifting the pancreas has to do breaking them down . If you consume high fat at one moment it puts stress on the pancreas and it doesn't matter what that fat is . Could be animal or plant based . If you couple that with high sugar which will put additional strain on the pancreas . As children this is your diet . Ice cream is a great example of high fat and sugar and eating this way puts strain on the pancreas into adulthood. I might say this is the biggest problem with cardiovascular health . My brother had pancreatitis multiple times and needed to be hospitalized . I had a possible bout but worked through it as I had an understanding on how to treat it because my dog had a severe case . The key is not to have a consumption of a lot of fat at one time . More than a slice of pizza may not be good and you add beer to that your pancreas will say no mass .
Coronary artery disease takes longer than the test perio😢
this guy is a gaslighter and super dangerous!
I seem to recall something about that Minnesota study. Wasn't it basically an aborted study that the author tried to cobble together enough data to publish something? The number of people was low, the average duration was only one year, dietary compliance was random.
No way they "only" changed the saturated vs unsaturated fat. Safflower oil and olive oil are very different, as is butter from lard. You're changing vitamin intake, polyphenols, among other things. So the problem isn't that the study is difficult to interpret, it is that the study isn't doing what it thinks it is doing and is confounded by numerous other variables
The study actually ran just a little more than 1 year, as I recall. Which makes it's results much less useful
https://youtu.be/taaEOY5E5Iw?si=ZgnXL1hwwzh545J3 this video explains the reason why no significant difference in outcomes were found
The average time for individuals spent on the Minnesota diet was actually 384 days. The whole thing was unworkable and virtually disbanded and is not credible at all. So much for Youtube.
Doesn't saturated fat activate inflammation via TLR4, increase mitochondria ROS by increasing reverse electron flow, and make cells more insulin resistant? In addition, don't saturated fats alter gut bacterial so as to increase inflammation?
Not only what is in in book… there are tons of talks on his podcast CLEARLY stating the fact that saturated fat is bad for cvd! Having one clip like this is what confuses people and is doing a disservice to the population as a whole!!!
FooLs
Algorithm
As a biochemist who teaches nutrition at a medical school, this video drives me crazy. You know Dayspring can answer this question way better than Layman. Why arent you having that discussion with Dayspring? Also, the Minnesota study was extremely flawed in that people were leaving the study early as they left the institution. That is why the results were not published- the study cohort fell apart. It had nothing to do with the results and hiding the data. There is really good mendalian randomization studies on saturated fat if you don't love the epidemiology. I don't know how you are missing these studies…..
Will you go to Heaven when you die? Have you lied, stolen, used God’s name in vain, or lusted (which Jesus said was adultery, Mt. 5:28)? If so, God sees you as a liar, thief, blasphemer, and adulterer at heart. If you die in your sins, you will end up in a terrible place called Hell. But there’s good news. Though we broke God’s Law, Jesus paid the fine by dying on the cross: “God so loved the world that He gave His only begotten Son, that whoever believes in Him should not perish but have everlasting life”
(Jn. 3:16). Then Jesus rose from the dead and was seen by hundreds of eyewitnesses. He fulfilled all the prophecies of the promised Saviour. Please, today, repent and trust Jesus, and God will forgive you and grant you the gift of eternal life (Eph. 2:8,9). Then, to show your gratitude, read the Bible daily and obey it, join a Christian church, and be baptized, you must be born again 😊✝🙏🏻
Shouldn't this video be between this video be between 2 experts? What a waste of time.
Come on. It’s not calorie number. Please 🙏. This is so wrong on such a respectable platform. It’s the quality not quantity
Attia once again showing he sees what he wants to see, it’s well known why he didn’t publish those results now. Video is a year old so hopefully he’s educated himself a bit since this video.
Too bad he ended with the importance of calories, when are we going to stop talking about macronutrients and calories and talk about the food itself! This redirects the conversation to whole foods, one in which a calorie surplus is more difficult to achieve. Yes, of course, calories matter, but the underlying cornerstone of that concept is that food quality matters. You get that right, and the calories fall into place, but in the meantime, we're still talking about secondary and tertiary points.
“I’m not a lipid expert”. Get a guest who can answer the question in the title. 😂
Ok makes sense to me? Why are people cross. If you don’t eat too many calories nothing suggesting getting calories from saturated fat is a bad thing. I’d say avoid UPF as this is what is too easy to eat in excess!
Yeah, but to be practical for just a moment, most Americans do eat too many calories. So, practically speaking, most Americans should go light on the saturated fat. They should go light on the calories, too, but let's be practical.
Please talk only about studies you know in detail!
After a personal 5-year N=1 study, I found exactly what Dr Layman stated at the end. Maintaining my daily calorie intake to what my body requires (along with daily exercise) was the key to getting my morning fasting glucose numbers down in the lower to mid-range of normal from the pre-diabetes range. Macronutrients are more or less evenly distributed.
Saturated fat isn’t the issue. We have to get this saturated fats thing out of our heat. No difference in events… the lower saturated fats would have fewer events. Calories and well, insulin spikes, in my thought, are what I am seeing as the issue.
Cures!!
I’d love to see Layne Norton get on with his fellow Don Layman because they disagree here. Would love to hear his perspective.